![]() was once upon a time the world’s biggest vaccine producer until the pandemic came along. The first company featured on our list which does not have a Covid-19 vaccine, Merck & Co. While it has since sold its shares, the two companies continue to work together on mRNA vaccines targeting tumors and cardiovascular illness. In 2014 Moderna partnered with AstraZeneca on a record deal worth US$240mn – the highest amount paid to a biotech that had never tested its products on humans. It is set to play an important role in booster programs this winter. Earlier this month the US biotech firm announced findings showing that its booster shot targeting the omicron variant produced an even stronger immune response than its original Covid-19 vaccine. ModernaĪnother key Covid-19 vaccine manufacturer, Moderna has been focusing most of its business on vaccine development since 2014. It has also developed immunizations for hepatitis A and B, mumps and has entered the veterinary market with a vaccine for animal rabies. In 2009 Sinovac became the first company to gain approval for a vaccine for the H1N1 strain of influenza. Meanwhile clinical trials of an omicron-focused booster shot are set to begin in China and Chile and the company is also developing a vaccine which will target three strains of the virus at once: the original coronavirus and delta and omicron variants. SinovacĬhinese firm Sinovac had a record year in 2021, quadrupling its sales thanks to its Covid-19 vaccine CoronaVac, the main vaccine administered to the population of China. Initial clinical trials began before the pandemic and are showing positive results, with BioNTech founder Uğur Şahin stating that an effective cancer vaccine could be ready as soon as 2030. Through its FixVac (which stands for ‘fixed vaccine’) platform, BioNTech is leveraging antigens specific to each type of cancer, particularly targeting patients with advanced, hard-to-treat disease. BioNTechīuilding on the technology it developed to create the Covid-19 vaccine with Pfizer, BioNTech is currently studying possible uses to treat melanoma among other forms of cancer. ![]() In 2015 the company acquired two vaccines that protect against meningitis from GSK. It began its collaboration with BioNTech in 2018, to research mRNA vaccines to treat influenza. While Comirnaty is its most well-known vaccine, Pfizer has also developed vaccinations for pneumonia, smallpox and polio. Now called Comirnaty, the vaccine has recently been authorized for use among infants aged six months old and up. The partnership between Pfizer and BioNTech which yielded one of the first approved vaccines for Covid-19 elevated the company’s revenue and profile dramatically. This wiped more than US$10bn off the market value of the two Covid-19 vaccine manufacturers.ĭespite this they remain among the world’s largest producers of vaccines, alongside the eight others this article outlines. ![]() When US President Joe Biden announced that the pandemic was over in a televised interview in September 2022, shares of Moderna and BioNTech swiftly dropped in value by up to 9 percent. ![]()
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